\u25cf Skin that feels thin, fragile or less resilient [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.14.2″ _module_preset=”default” custom_margin_tablet=”” custom_margin_phone=”||-30px||false|false” custom_margin_last_edited=”on|phone” custom_padding=”||||false|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.14.2″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/drpreema.com\/wp-content\/uploads\/2024\/04\/Polynucleotides3-before-and-after-treatment-at-Dr-Preema-London-Clinic.jpg” alt=”Before and after results showing reduced fine lines, smoother texture, and improved skin tone around the eyes following polynucleotide treatment at Dr Preema London Clinic.” title_text=”Polynucleotides3 before and after treatment at Dr Preema London Clinic” align=”center” _builder_version=”4.14.2″ _module_preset=”default” max_height=”480px” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.14.2″ _module_preset=”default” custom_margin_tablet=”” custom_margin_phone=”||-30px||false|false” custom_margin_last_edited=”on|phone” custom_padding=”||||false|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.14.2″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.14.2″ _module_preset=”default” header_font=”Montserrat||||||||” header_2_font=”Prata||||||||” header_3_font=”Prata||||||||” custom_margin=”||||false|false” custom_margin_tablet=”||||false|false” custom_margin_phone=”0px||||false|false” custom_margin_last_edited=”on|phone” custom_padding=”10px||||false|false” custom_padding_tablet=”30px||||false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|phone” inline_fonts=”Montserrat” global_colors_info=”{}”]<\/p>\n [\/et_pb_text][et_pb_text _builder_version=”4.14.2″ _module_preset=”default” header_3_font=”Prata||||||||” hover_enabled=”0″ inline_fonts=”Montserrat” global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n Polynucleotides<\/a> are fundamentally different from both Profhilo and Revitalis.<\/span><\/p>\n Rather than acting primarily as a hydrator or skin supporter, Polynucleotides work at a cellular level to stimulate repair, regeneration and tissue healing. Derived from highly purified DNA fragments, they help to:<\/span><\/p>\n \u25cf Improve skin repair and recovery Polynucleotides<\/a> are particularly valuable in delicate or compromised areas, such as the under-eye region, neck, or skin that has been weakened by ageing, inflammation or previous treatments.<\/span><\/p>\n Best suited for:<\/span><\/p>\n \u25cf Crepey or fragile skin Polynucleotides do not replace Profhilo or Revitalis. Instead, they address a different biological process \u2014 skin regeneration rather than hydration or structural support. [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.14.2″ _module_preset=”default” custom_margin_tablet=”” custom_margin_phone=”||-30px||false|false” custom_margin_last_edited=”on|phone” custom_padding=”||||false|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.14.2″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/drpreema.com\/wp-content\/uploads\/2026\/02\/Profhilo-Body-treatment-with-Dr-Preema-Vig.jpg” alt=”Profhilo Body treatment being performed by Dr Preema Vig to improve skin quality, firmness and hydration on the body.” title_text=”Profhilo Body treatment with Dr Preema Vig” align=”center” _builder_version=”4.14.2″ _module_preset=”default” max_height=”480px” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.14.2″ _module_preset=”default” custom_margin_tablet=”” custom_margin_phone=”||-30px||false|false” custom_margin_last_edited=”on|phone” custom_padding=”||||false|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.14.2″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.14.2″ _module_preset=”default” header_font=”Montserrat||||||||” header_2_font=”Prata||||||||” header_3_font=”Prata||||||||” custom_margin=”||||false|false” custom_margin_tablet=”||||false|false” custom_margin_phone=”0px||||false|false” custom_margin_last_edited=”on|phone” custom_padding=”10px||||false|false” custom_padding_tablet=”30px||||false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|phone” inline_fonts=”Montserrat” global_colors_info=”{}”]<\/p>\n [\/et_pb_text][et_pb_text _builder_version=”4.14.2″ _module_preset=”default” header_3_font=”Prata||||||||” hover_enabled=”0″ inline_fonts=”Montserrat” global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n The confusion arises because all three treatments:<\/span><\/p>\n \u25cf Are injectable However, their mechanisms of action are entirely different:<\/span><\/p>\n \u25cf Profhilo<\/a> hydrates and remodels the dermis One does not replace the other \u2014 they simply address different skin needs. <\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.14.2″ _module_preset=”default” custom_margin_tablet=”” custom_margin_phone=”||-30px||false|false” custom_margin_last_edited=”on|phone” custom_padding=”||||false|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.14.2″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/drpreema.com\/wp-content\/uploads\/2026\/02\/The-Dr-Preema-Method.jpg” alt=”Dr Preema Vig demonstrating The Dr Preema Method at her Mayfair clinic, combining expert consultation with personalised non-surgical aesthetic treatments.” title_text=”The Dr Preema Method” align=”center” _builder_version=”4.14.2″ _module_preset=”default” max_height=”480px” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.14.2″ _module_preset=”default” custom_margin_tablet=”” custom_margin_phone=”||-30px||false|false” custom_margin_last_edited=”on|phone” custom_padding=”||||false|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.14.2″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.14.2″ _module_preset=”default” header_font=”Montserrat||||||||” header_2_font=”Prata||||||||” header_3_font=”Prata||||||||” custom_margin=”||||false|false” custom_margin_tablet=”||||false|false” custom_margin_phone=”0px||||false|false” custom_margin_last_edited=”on|phone” custom_padding=”10px||||false|false” custom_padding_tablet=”30px||||false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|phone” inline_fonts=”Montserrat” global_colors_info=”{}”]<\/p>\n [\/et_pb_text][et_pb_text _builder_version=”4.14.2″ _module_preset=”default” header_3_font=”Prata||||||||” hover_enabled=”0″ inline_fonts=”Montserrat” global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n Many patients achieve excellent results with Profhilo<\/a>, Revitalis or Polynucleotides<\/a> as standalone treatments \u2014 and in many cases, this is exactly the right approach.<\/span><\/p>\n At Dr Preema London Clinic, we also consider how results can be supported and optimised over time. The Dr Preema Method is our personalised way of planning treatments thoughtfully, selecting and timing them to work in harmony with the skin when clinically appropriate.<\/span><\/p>\n While Profhilo<\/a> and Revitalis are not used together, either may be carefully layered with Polynucleotides<\/a> to support skin quality, resilience and repair. This allows us to address hydration or structure alongside cellular regeneration, helping to create results that look natural, balanced and long-lasting.<\/span><\/p>\n Every treatment plan begins with a detailed medical consultation, ensuring recommendations are guided by your skin\u2019s needs, your goals, and long-term skin health \u2014 not trends or templates.<\/span>\u00a0<\/span><\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.14.2″ _module_preset=”default” custom_margin_tablet=”” custom_margin_phone=”||-30px||false|false” custom_margin_last_edited=”on|phone” custom_padding=”||||false|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.14.2″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.14.2″ _module_preset=”default” header_font=”Montserrat||||||||” header_2_font=”Prata||||||||” header_3_font=”Prata||||||||” custom_margin=”||||false|false” custom_margin_tablet=”||||false|false” custom_margin_phone=”0px||||false|false” custom_margin_last_edited=”on|phone” custom_padding=”10px||||false|false” custom_padding_tablet=”30px||||false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|phone” inline_fonts=”Montserrat” global_colors_info=”{}”]<\/p>\n [\/et_pb_text][et_pb_text _builder_version=”4.14.2″ _module_preset=”default” header_3_font=”Prata||||||||” hover_enabled=”0″ inline_fonts=”Montserrat” global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n Profhilo<\/a>, Revitalis and Polynucleotides<\/a> are all established, evidence-led treatments \u2014 and each is very much here to stay. One has not replaced another; instead, each continues to play a distinct role within modern aesthetic medicine when used for the right indication.<\/span><\/p>\n Understanding these differences allows treatments to be selected thoughtfully, rather than driven by trends. Whether used as standalone options or layered intelligently, the goal is always the same: to support skin health, resilience and natural-looking results over time.<\/span><\/p>\n To explore which approach is most appropriate for your skin, you can book a consultation with Dr Preema, or if you have questions before coming in, chat with Dr Preema AI for guidance and education ahead of your visit. <\/p>\n <\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" In the world of aesthetic treatments, Revitalis, Profhilo and Polynucleotides are often grouped together \u2014 yet they are frequently misunderstood or assumed to serve the same purpose. In reality, each works in a very different way, targets different layers of the skin, and is used for distinct clinical indications. At Dr Preema London Clinic, education […]<\/p>\n","protected":false},"author":5,"featured_media":5100,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_seopress_robots_primary_cat":"none","_seopress_titles_title":"Profhilo, Polynucleotides & Revitalis: Which Skin Booster Is Right for You? | Dr Preema London Clinic","_seopress_titles_desc":"Confused by Profhilo, Polynucleotides or Revitalis? Dr Preema explains the key differences between today\u2019s leading injectable skin boosters and how to choose the right option for your skin.","_seopress_robots_index":"","_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"2880","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[3],"tags":[],"class_list":{"0":"post-55389","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-blog"},"jetpack_featured_media_url":"https:\/\/i0.wp.com\/drpreema.com\/wp-content\/uploads\/2021\/06\/Profhilo-Lower-face-watermark-1.jpg?fit=2321%2C1193&ssl=1&wsr","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/drpreema.com\/ar\/wp-json\/wp\/v2\/posts\/55389","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/drpreema.com\/ar\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/drpreema.com\/ar\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/drpreema.com\/ar\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/drpreema.com\/ar\/wp-json\/wp\/v2\/comments?post=55389"}],"version-history":[{"count":9,"href":"https:\/\/drpreema.com\/ar\/wp-json\/wp\/v2\/posts\/55389\/revisions"}],"predecessor-version":[{"id":55476,"href":"https:\/\/drpreema.com\/ar\/wp-json\/wp\/v2\/posts\/55389\/revisions\/55476"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/drpreema.com\/ar\/wp-json\/wp\/v2\/media\/5100"}],"wp:attachment":[{"href":"https:\/\/drpreema.com\/ar\/wp-json\/wp\/v2\/media?parent=55389"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/drpreema.com\/ar\/wp-json\/wp\/v2\/categories?post=55389"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/drpreema.com\/ar\/wp-json\/wp\/v2\/tags?post=55389"}],"curies":[{"name":"\u0648\u0648\u0631\u062f\u0628\u0631\u064a\u0633","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\u25cf Patients concerned about long-term skin ageing
\u25cf Those seeking improved firmness and structural support rather than hydration alone<\/span>\u00a0<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\nPolynucleotides: Cellular Repair & Skin Regeneration<\/span><\/h2>\n
\u25cf Enhance tissue quality
\u25cf Support collagen production
\u25cf Calm inflammation
\u25cf Improve skin texture and tone<\/span><\/p>\n
\u25cf Under-eye rejuvenation
\u25cf Post-treatment recovery
\u25cf Improving skin vitality and repair<\/span><\/p>\n
<\/span><\/p>\nWhy They\u2019re Often Confused \u2014 And Why They\u2019re Not Interchangeable<\/span><\/h2>\n
\u25cf Improve skin quality
\u25cf Do not create traditional filler volume<\/span><\/p>\n
\u25cf Revitalis strengthens and supports skin structure
\u25cf Polynucleotides<\/a> regenerate and repair at a cellular level<\/span><\/p>\n
<\/span><\/p>\nThe Dr Preema Method: Thoughtful Treatment Layering<\/span><\/h2>\n
Final Thoughts<\/span><\/h2>\n
<\/span><\/p>\n