Black and white close-up of a shocked woman covering her mouth, reacting to changes associated with Ozempic face

Understanding “Ozempic Face” and “Mounjaro Face”

How Rapid Weight Loss Can Affect Facial Volume — and How We Can Help at Dr Preema London Clinic

In recent years, injectable weight-loss medications such as Ozempic (semaglutide) and Mounjaro (tirzepatide) have transformed the way people manage their health and body composition. While these medications can be life-changing, a lesser-known aesthetic side effect has emerged — often referred to as “Ozempic Face” or “Mounjaro Face.”

At Dr Preema London Clinic in Mayfair, we are seeing an increasing number of patients experiencing facial changes following rapid weight loss. Our doctor-led, holistic approach allows us to restore balance, definition and vitality safely and naturally.

Woman touching her temples with facial lifting guide lines illustrating sagging and contour changes linked to Ozempic face

What Is “Ozempic Face”?

“Ozempic Face” or “Mounjaro Face” describes a change in facial appearance that can follow significant, rapid weight loss.

As body fat reduces quickly, the natural facial fat pads that support and shape the face can also diminish. This may result in:

• Hollow or sunken cheeks

• Loss of mid-face fullness

• More visible fine lines and skin laxity

• A tired or prematurely aged appearance

It’s important to note that these changes are not caused directly by the medication itself, but by the speed of weight loss and the skin’s ability to adapt to the new structure.

Why It Happens

Youthful facial contours depend on a delicate balance of bone structure, muscle tone, fat distribution and skin elasticity.

When weight is lost rapidly, the face can lose structural volume faster than the skin can contract or remodel. This imbalance leads to laxity, folds and loss of definition around the cheeks, jawline and eyes.

Age, genetics and pre-existing skin quality also play a part — which is why the effects vary between individuals.

Aesthetic practitioner administering cheek filler injection while a woman rests with her eyes closed

How We Can Help

At Dr Preema London Clinic, our philosophy is centred on restoring harmony, structure and vitality to the skin using advanced, non-surgical techniques. Each plan begins with a comprehensive Aura Skin Scan, allowing us to assess facial structure, volume loss and skin quality in detail before tailoring a bespoke rejuvenation programme.

1. Skin Quality & Collagen Support

Before addressing lost volume, we first focus on strengthening the skin’s foundation. Treatments such as Sylfirm X RF Microneedling and Sofwave Ultrasound Skin Tightening stimulate collagen and elastin, improving firmness and resilience.

These modalities help the skin appear smoother, tighter and better able to hold restored volume naturally.

2. Volume Restoration & Structural Rebalance

Once skin quality is optimised, we address the loss of support within the mid-face and lower-face regions.

• Profhilo Structura: the next-generation bioremodeller that restores deep structural support while improving elasticity. Unlike traditional fillers, it integrates with tissue to redefine contours while maintaining natural expression.

• Polynucleotides: regenerative injectables that improve skin quality, hydration and repair at a cellular level.

• Advanced Dermal Fillers: applied using micro-cannula or precision needle techniques to restore balance and lift without heaviness or distortion.

Every plan is personally designed by Dr Preema Vig to enhance individual features, prioritising subtle, elegant and authentic results.

3. Ongoing Maintenance & Care

Facial rejuvenation following rapid weight loss often benefits from a staged approach. Once weight has stabilised, regular reviews help refine results and maintain facial integrity.

At this stage, supportive treatments such as Exosomes, LED Light Therapy, and medical-grade skincare can be introduced to preserve elasticity, glow and overall skin health.

Two aesthetic practitioners standing at a luxury clinic reception desk, smiling in a modern, elegant setting

Why Choose Dr Preema London Clinic

Our Mayfair clinic combines medical expertise with a discreet, luxury environment dedicated to advanced facial rejuvenation. Dr Preema Vig — a former GP with over 20 years’ experience in aesthetics — leads every treatment plan with precision and care. From diagnostic analysis to regenerative treatments and structural bioremodelling, we offer a holistic pathway to restore facial harmony and confidence safely, naturally and beautifully.

Book Your Consultation

If you have noticed facial changes following rapid weight loss or GLP-1 medication, our expert team can help restore your natural contours and skin vitality.

Contact Dr Preema London Clinic on 020 7221 0043 or click here to arrange your consultation.

Frequently Asked Questions

❓Can you reverse “Ozempic Face” or “Mounjaro Face”? Yes — while it’s not possible to “reverse” weight-related facial changes entirely, it is possible to restore lost volume, improve firmness and rejuvenate skin quality. At Dr Preema London Clinic, we use regenerative treatments such as Profhilo Structura, Polynucleotides and Sylfirm X RF Microneedling to rebuild collagen and redefine facial contours, achieving natural, harmonious results.

❓Which treatments can help restore facial volume after weight loss? A bespoke combination of bio-remodelling, regenerative and collagen-stimulating treatments can restore natural facial structure. This may include Profhilo Structura, Polynucleotides, advanced dermal fillers, and Sofwave Ultrasound Skin Tightening — all designed to lift, firm and re-sculpt the face without surgery.

❓How soon after weight loss can I have treatment?

It’s best to wait until your weight has stabilised for several weeks before starting volume restoration. This ensures that results are balanced and long-lasting. During your consultation, Dr Preema will assess skin quality and advise on the most suitable timing and treatment sequence.

❓Are the results natural-looking? Yes. Dr Preema approach is known for subtle, elegant and natural-looking results. Treatments are performed using precision techniques that enhance your own facial features rather than alter them, ensuring a refreshed and authentic appearance.

❓Why choose Dr Preema London Clinic for facial rejuvenation? As a doctor-led clinic in Mayfair, we combine medical expertise with advanced aesthetic technologies to deliver safe, effective and beautifully natural outcomes. Dr Preema brings over two decades of experience in non-surgical rejuvenation and a deeply personalised approach to every patient.

Understanding Ozempic Face and Mounjaro Face