Where Can Profhilo Be Used? The Key Treatment Areas Explained
Profhilo has become one of the most talked-about injectable treatments for improving skin quality. Rather than altering facial shape or adding volume, Profhilo focuses on enhancing the skin itself — supporting hydration, elasticity and overall skin health.
At Dr Preema London Clinic in Mayfair, Profhilo is frequently incorporated into personalised treatment plans using The Dr Preema Method, a layered approach designed to deliver natural-looking results while supporting long-term skin quality.
But many patients ask the same question: where can Profhilo actually be used?
While the face is the most commonly treated area, Profhilo can also be used on several parts of the body where skin quality, laxity or crepey texture are concerns.
What Is Profhilo?
Profhilo is an injectable treatment containing one of the highest concentrations of stabilised hyaluronic acid used in aesthetic medicine.
Unlike dermal fillers, which are designed to add volume or reshape facial features, Profhilo works through a process known as bio-remodelling. Once injected, it spreads beneath the skin to stimulate collagen and elastin while deeply hydrating the tissue.
In recent years, the Profhilo range has expanded to address different skin concerns and treatment areas:
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- Profhilo – the original injectable treatment used to improve skin quality on the face, neck and hands.
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- Profhilo Body – developed to support skin laxity and hydration in larger areas of the body such as the abdomen, arms and knees.
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- Profhilo Structura – a newer treatment designed to support deeper facial structures and help address changes in facial fat compartments that occur with ageing.
Together, these treatments support a regenerative approach to improving skin quality across both the face and body.
Profhilo for the Face
The face is the most recognised treatment area for Profhilo.
Rather than targeting individual lines or wrinkles, Profhilo is injected at carefully mapped points that allow the product to diffuse beneath the skin. This supports improvements in hydration, elasticity and overall skin quality.
Patients often notice:
• improved skin luminosity
• smoother texture
• better hydration
• a more refreshed overall appearance
For patients experiencing deeper structural changes in the mid-face or lower face, Profhilo Structura may sometimes be considered as part of a personalised treatment plan.
Profhilo for the Forehead
Some patients also ask whether the forehead can be treated with Profhilo.
In selected cases, carefully placed injections may help improve skin hydration, texture and overall skin quality across the upper face. Patients concerned with dullness, fine lines or crepey skin in the forehead area may benefit from the regenerative effects of hyaluronic acid bio-remodelling.
However, the forehead requires particular clinical expertise due to the anatomy of the area. For this reason, treatment in this region should always be carefully assessed and performed by an experienced medical practitioner.
At Dr Preema London Clinic, every treatment plan begins with a detailed consultation to determine the most appropriate and safest approach for each patient.
Profhilo for the Neck
The neck is often one of the first areas to show visible signs of ageing due to thinner skin and constant movement.
Profhilo can help improve:
• fine lines
• crepey texture
• reduced skin elasticity
• dehydration
Treating the neck alongside the face often helps maintain a more balanced and natural-looking rejuvenation.
Profhilo for the Arms and Knees
Areas such as the upper arms and knees are often where skin laxity and crepey texture become more noticeable over time. These areas can be difficult to address with topical skincare alone, which is why many patients explore regenerative injectable treatments to improve skin quality.
Profhilo is well suited to these areas because it works by deeply hydrating the skin while stimulating collagen and elastin production, helping to improve elasticity and overall skin integrity.
Patients commonly seek treatment here to address:
• crepey skin on the upper arms
• loss of firmness around the knees
• skin thinning and reduced elasticity
• overall improvements in skin hydration and texture
For larger treatment areas on the body, Profhilo Body may also be incorporated to support broader improvements in skin quality and structural support.
Profhilo for the Hands
The hands can reveal age through thinning skin and reduced elasticity.
Profhilo helps restore hydration and improve skin texture, allowing the hands to appear smoother and healthier without affecting natural movement.
For patients concerned about skin laxity across the forearms or upper arms, Profhilo Body may also be considered as part of a broader treatment plan.
Profhilo for Crepey Skin
Crepey skin can develop in several areas of the body where collagen and elastin naturally decline over time.
Common areas include:
• upper arms
• abdomen
• knees
Profhilo works by supporting collagen and elastin production within the skin, helping improve overall texture and hydration.
For facial areas where skin laxity is linked to deeper structural changes, Profhilo Structura may be used to support tissue quality at a deeper level.
Profhilo vs Skin Boosters: What’s the Difference?
Patients often ask how Profhilo compares with traditional skin boosters and other injectable treatments designed to improve skin quality.
While both treatments contain hyaluronic acid and aim to enhance hydration, they work in different ways.
Skin boosters are typically placed in multiple small deposits across the skin to deliver hydration locally and improve superficial skin texture.
Profhilo spreads beneath the skin and stimulates bio-remodelling, helping the skin improve its own collagen and elastin production. This makes it particularly suited to addressing overall skin quality and early skin laxity.
Some patients also compare Profhilo with Polynucleotides, another regenerative injectable treatment. Polynucleotides focus more on cellular repair and tissue regeneration, while Profhilo works by deeply hydrating the skin and stimulating collagen and elastin production.
At Dr Preema London Clinic, treatments are selected and layered using The Dr Preema Method, ensuring the most appropriate regenerative approach is chosen for each patient’s individual skin needs.
Is Profhilo Worth It?
For patients seeking subtle, natural-looking improvements in skin quality, Profhilo can be an excellent option.
It is particularly suitable for those who:
• want to improve hydration and skin texture
• are noticing early skin laxity
• prefer regenerative treatments rather than volume-based approaches
• want refreshed, natural-looking results
As with all aesthetic treatments, outcomes are best achieved through personalised treatment planning.
How Many Profhilo Treatments Do You Need?
Profhilo is typically performed as a course of two treatments, spaced around four weeks apart. This protocol helps stimulate the skin’s natural regenerative processes, encouraging improvements in hydration, elasticity and overall skin quality.
Following the initial course, many patients choose to have maintenance treatments every six to twelve months, depending on their skin concerns and long-term treatment goals.
At Dr Preema London Clinic, treatment plans are always tailored to the individual. Factors such as skin quality, age, lifestyle and the areas being treated can all influence the recommended approach.
For some patients, Profhilo may form part of a broader regenerative plan using The Dr Preema Method, where treatments are layered strategically to support collagen stimulation and long-term skin health.
The Dr Preema Method: A Personalised Approach
At Dr Preema London Clinic, treatments such as Profhilo are often integrated into broader treatment plans using The Dr Preema Method.
This layered approach combines regenerative treatments and advanced technologies to support long-term skin health while maintaining natural facial harmony.
Discover Whether Profhilo Is Right for You
If you are considering Profhilo and would like to explore whether it may be suitable for your skin concerns, our team at Dr Preema London Clinic in Mayfair would be delighted to help.
You can begin by booking a consultation with one of our experienced practitioners, who will guide you through the most appropriate treatment options for your skin.
Book your consultation online here.
You can also begin your personalised journey using Dr Preema AI, our digital consultation tool designed to guide you through potential treatment options before visiting the clinic.
Written by the team at Dr Preema London Clinic
Medically reviewed by Dr Preema Vig, Medical Director
