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Skin Boosters & Collagen Stimulating Injectables | London

At Dr Preema London Clinic in Mayfair, we offer a range of advanced skin boosters and collagen stimulating injectable treatments designed to improve skin quality, hydration and overall skin health. Often referred to as skin boosters, modern regenerative injectables such as Profhilo, Sunekos, Polynucleotides and Revitalis work by supporting the skin’s natural repair processes, stimulating collagen production and enhancing elasticity. Rather than simply adding volume, these treatments focus on restoring skin quality from within, helping to improve texture, luminosity and firmness.

What Are Skin Boosters?

Skin boosters are injectable treatments designed to improve skin quality, hydration and elasticity from within. Unlike traditional dermal fillers, which are used to restore volume or reshape facial features, skin boosters work by enhancing the skin itself — helping to improve texture, luminosity and overall skin health.

Many modern skin boosters are now considered collagen stimulating or regenerative injectables, meaning they do more than simply hydrate the skin. Treatments such as Profhilo, Sunekos, Polynucleotides and Revitalis are designed to support the skin’s natural repair processes, stimulate collagen and elastin production, and improve structural integrity over time.

These treatments are commonly used to address concerns such as:

• loss of skin hydration
• fine lines and crepey skin
• reduced elasticity
• dull or uneven skin texture
• early skin laxity

Skin boosters can be used across a range of areas including the face, neck, décolletage, hands and body, helping to restore healthier, more resilient skin.

Dr Preema Vig holding a syringe at Dr Preema London Clinic in Mayfair, London, demonstrating doctor-led injectable aesthetics.

Profhilo Treatments: Profhilo, Profhilo Body & Profhilo Structura

Profhilo is one of the most recognised skin booster and collagen stimulating injectable treatments, designed to improve overall skin quality rather than add volume. Formulated with highly purified hyaluronic acid, Profhilo spreads beneath the skin to stimulate collagen and elastin production while delivering deep hydration. This process, known as bio-remodelling, helps improve skin texture, elasticity and luminosity, making it particularly popular for treating areas such as the face, neck and hands where skin quality may begin to decline.

For concerns affecting larger areas of the body, Profhilo Body has been specifically developed to target skin laxity and crepey skin on areas such as the abdomen, upper arms and knees. Using a similar regenerative approach, Profhilo Body works to improve skin firmness and elasticity while supporting healthier, more resilient skin over time.

A newer evolution of the treatment, Profhilo Structura, has been designed to support deeper tissue structure and facial contour. Rather than simply improving hydration within the skin, Profhilo Structura works within deeper tissue layers to help restore structural support, making it particularly suited to concerns such as facial volume loss and skin laxity associated with ageing.

As facial ageing progresses, structural changes within the fat compartments can lead to a loss of shape and definition. Profhilo Structura is designed to work within these deeper layers, supporting tissue integrity and helping to maintain a more balanced, naturally contoured appearance over time.

For more detailed information about treatment protocols, suitability and results, please visit our dedicated Profhilo treatment page.

Alt text: Before and after Profhilo facial treatment showing improved skin hydration, smoother texture and enhanced skin quality at Dr Preema London Clinic Mayfair

Profhilo Face and Profhilo Body treatment results at Dr Preema London Clinic – real patient results demonstrating improved hydration, firmness and elasticity across the face and abdomen, with natural-looking enhancement of overall skin quality.

Before and after images showing improved abdominal skin texture and laxity treated with Profhilo Body at Dr Preema London.

Polynucleotide Skin Treatments

Polynucleotides are advanced regenerative injectable treatments designed to support skin repair, improve tissue quality and stimulate collagen production. Derived from highly purified DNA fragments, polynucleotides work by encouraging the skin’s natural regeneration processes, helping to improve hydration, elasticity and overall skin resilience over time.

Unlike some injectable treatments that focus primarily on hydration, polynucleotides are particularly valued for their ability to support cellular repair and skin regeneration. This makes them a popular choice for patients looking to improve skin texture, fine lines and overall skin quality, while also strengthening the skin’s natural barrier function.

Polynucleotides are especially well suited to delicate areas where skin quality is often a concern, including the under-eye area, face, neck and décolletage. They can help improve concerns such as fine lines, crepey skin, dullness and reduced elasticity, while supporting healthier, more resilient skin.

For more detailed information about treatment protocols, benefits and suitability, please visit our dedicated Polynucleotides treatment page.

Before and after polynucleotide eye treatment – front view showing improvement in under eye skin quality, smoother texture and refreshed appearance at Dr Preema London Clinic, Mayfair London.

Polynucleotide treatment results at Dr Preema London Clinic – real patient results demonstrating improved skin quality, hydration and elasticity, with a smoother, brighter and more resilient appearance.

Before and after results showing reduced fine lines, smoother texture, and improved skin tone around the eyes following polynucleotide treatment at Dr Preema London Clinic.

Revitalis Treatment

Revitalis is a regenerative injectable treatment designed to improve skin quality, hydration and collagen stimulation while supporting the skin’s natural repair processes. Classified as a collagen stimulating injectable, Revitalis works by encouraging the skin to regenerate and strengthen over time, helping to improve overall skin texture, elasticity and resilience.

The treatment is particularly effective for patients looking to address fine lines, loss of skin firmness and early skin laxity, while maintaining natural-looking results. By supporting the skin’s underlying structure and hydration levels, Revitalis helps restore a healthier, more radiant appearance without adding volume.

Revitalis can be used across a range of areas where skin quality is a concern, including the face, neck and décolletage. It is often chosen by patients seeking a regenerative approach to skin rejuvenation, particularly when the goal is to improve skin strength, hydration and elasticity over time.

As with many collagen stimulating injectable treatments, Revitalis is typically delivered as a course of treatments, allowing the skin to gradually respond to the regenerative process and build long-term improvements in skin quality.

Before and after abdomen skin tightening treatment at Dr Preema London Clinic, showing improved skin firmness, smoother texture and reduced creasing following a bespoke non-surgical body protocol.

Revitalis treatment results at Dr Preema London Clinic – real patient results showing improved skin firmness, texture and overall quality across the abdomen, with a smoother and more refined appearance.

Sunekos Treatment

Sunekos is an advanced injectable treatment designed to improve skin quality, elasticity and overall skin health by stimulating the skin’s natural regenerative processes. Unlike many traditional skin boosters that focus primarily on hydration, Sunekos combines hyaluronic acid with a patented blend of amino acids that work together to stimulate the production of collagen and elastin within the skin.

This unique formulation supports the extracellular matrix, the structure responsible for maintaining skin strength, hydration and elasticity. By helping to restore this balance, Sunekos can improve fine lines, skin texture, elasticity and overall skin quality, making it a popular choice for patients seeking subtle, natural-looking skin rejuvenation.

One of the key advantages of Sunekos is its suitability for delicate areas where skin quality is often a concern. It is frequently used to treat the under-eye area, face, neck and décolletage, helping to improve concerns such as fine lines, crepey skin and early skin laxity.

Sunekos is typically delivered as a course of treatments, allowing the skin to gradually regenerate and strengthen over time. Many patients choose Sunekos when they are looking to improve skin quality and collagen stimulation without adding volume, particularly in areas where traditional dermal fillers may not be appropriate.

 

Discover more on our Blog page, including:

What is the difference between Profhilo and Profhilo Structura?
Read our blog for a detailed explanation.

Comparing skin-boosting injectables?
Our latest article explores Revitalis, Profhilo and Polynucleotides.

The Dr Preema Method

The Dr Preema Method is a personalised, layered approach to improving skin quality, structure and long-term resilience. Rather than relying on a single treatment, carefully selected technologies and injectables are combined and sequenced to support the skin at each stage — optimising results while maintaining a strong focus on skin health, safety and recovery.

Skin boosters and collagen-stimulating injectables such as Profhilo, Polynucleotides and Revitalis each play a distinct role within this approach.

Used alone, they can effectively target concerns such as dehydration, loss of elasticity or declining skin quality. When layered within a bespoke treatment plan, their benefits can be further enhanced:

With Polynucleotides
Support skin repair, resilience and recovery at a cellular level, making them particularly effective for fragile, sensitised or depleted skin.

With Profhilo
Improve hydration and elasticity, enhancing overall skin quality and creating a healthier foundation for further treatment.

With Revitalis
Provide structural support and stimulate collagen production, helping to restore firmness and long-term skin integrity.

With Energy-Based Devices (e.g. Sylfirm X or Sofwave)
Injectables improve skin quality and function, while devices stimulate deeper collagen remodelling and address texture or laxity — delivering a more comprehensive result.

By layering treatments in this way — or selecting a single injectable where appropriate — The Dr Preema Method allows each plan to be tailored with precision, supporting natural-looking, progressive and long-lasting results.

 

At a glance

Appointment Time

30 minutes

 

Comfort level

Comfortable. Numbing cream can be applied where required

Action to take effect

Immediate

Number of Treatments

Usually 2-3 treatments depending on skin concern & product used

Duration of effect

Up to six months

+44 (0)20 7221 0043

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Dr. Preema London Clinic

Avenfield House

118-127 Park Lane

Mayfair

London

W1K 7AF

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