Profhilo Structura London
Regenerative Facial Support & Skin Rejuvenation in Mayfair
Restore facial definition, tissue quality, and structural support naturally at Dr Preema London Clinic. We utilise Profhilo Structura in London as part of our advanced regenerative approach to facial ageing, helping to support skin quality and facial architecture without creating an overfilled or artificial appearance.
As we age, structural changes within the deeper facial fat compartments lead to skin heaviness, mid-face flattening, and a loss of jawline definition. Profhilo Structura is formulated specifically to target these deep structural changes using highly stabilised Hyaluronic Acid (HA), improving tissue integrity and restoring facial contours.
What Is Profhilo Structura?
Profhilo Structura is an advanced regenerative injectable treatment designed to target deeper, age-related structural changes within the face. Specifically addressing skin laxity, facial flattening, and mid-face volume loss.
Formulated by IBSA Derma using thermal NAHYCO® Hybrid Technology, Profhilo Structura features a ultra-high concentration of stabilised Hyaluronic Acid (HA) without chemical cross-linking agents (like BDDE). Unlike standard Profhilo, which targets superficial dermal hydration, Structura is engineered to restore and regenerate superficial facial fat compartments (adipose tissue).
Rather than creating artificial volume or drastically altering facial features like traditional dermal fillers, Profhilo Structura reposition and supports deep tissue in a subtle, natural-looking way.
Is Profhilo Structura Right for You?
At our Mayfair aesthetic clinic, Profhilo Structura is recommended for patients experiencing:
- Facial heaviness or early jowl formation
- Mid-face flattening and reduced cheek definition
- Softer jawline definition and sagging lower face
- Loss of skin firmness, elasticity, and structural support
- Ozempic or weight-loss related facial volume loss
Unlike traditional dermal fillers, Profhilo Structura does not add unnatural volume or alter your natural facial shape. Instead, it focuses on deep tissue repositioning, collagen stimulation, and subtle, natural-looking rejuvenation.
How Does Profhilo Structura Work?
Facial ageing is more than skin deep. Beyond surface-level fine lines, the superficial fat compartments beneath the skin naturally thin and shift over time. This underlying loss of support is what causes mid-face flattening, early jowl formation, and a tired, heavy appearance.
Profhilo Structura addresses this root cause using advanced NAHYCO® Hybrid Technology. Formulated with a higher concentration of thermal-stabilised Hyaluronic Acid (90mg/2ml), it works directly within the subcutaneous fat layer to restore structural integrity rather than masking the problem.
The Science Behind Profhilo Structura
Adipose Tissue Regeneration: Unlike surface-level skin boosters, Structura targets the superficial fat layer to signal fat cell regeneration and repositioning.
Biostimulation & Firmness: Triggers your body’s natural production of collagen and elastin to improve overall skin density and firmness.
Cannula-Led Comfort: Placed deep using a microcannula technique (instead of multiple needle punctures), ensuring precise delivery, minimal downtime, and less risk of bruising.
Structural Support vs. Volumising Fillers
Traditional dermal fillers add volume or sculpt sharp contours. Profhilo Structura takes a bio-regenerative approach. It acts as an invisible scaffold beneath the skin, giving your face a firmer, better-supported, and naturally refreshed foundation without changing your expression.
What areas can Profhilo Structura treat?
At Dr Preema London Clinic, Profhilo Structura is primarily used to restore areas of the face affected by reduced definition, tissue laxity, and structural fat pad atrophy. Unlike standard Profhilo (which targets surface skin quality), Structura is specifically indicated to regenerate deeper subcutaneous fat compartments in the mid and lower face.
Targeted treatment areas include:
| Treatment area | What Profhilo Structura may help with | How treatment is used in this area | Key limitations / considerations |
|---|---|---|---|
| Mid-Face | Mid-face flattening, loss of cheek definition, and reduced structural support due to age-related changes. | Used to target deeper subcutaneous tissue, helping to restore firmness, support facial structure, and elevate a flattening mid-face. | Designed to restore natural support rather than project sharp cheekbones. Patients seeking high-volume augmentation may require traditional dermal fillers. |
| Lower Face | Early facial heaviness, mild jowl formation, and declining tissue quality through the lower facial third. | Used to reinforce tissue integrity and support areas where skin laxity creates a heavier or less lifted appearance. | Aims to improve tissue quality and firmness. It is not a surgical facelift substitute for severe lower-face skin laxity. |
| Jawline Area | Softer jawline definition and early structural shifts along the lower contour. | Forms part of a subtle treatment plan to redrape and support tissue along the jawline for a cleaner profile. | Provides soft, natural framing rather than a sharp, squared-off jawline. Works best in early-to-moderate structural descent. |
| Overall Contour | General loss of facial definition, structural sagging, and a tired or unsupported facial architecture. | Applied strategically across anatomical support points to encourage a balanced, naturally defined, and refreshed appearance. | Treatment is intended to restore subtle harmony without creating an overfilled or exaggerated look. |
Profhilo Structura Treatment Protocol
Advanced regenerative injectable treatment designed to restore deep tissue support, facial architecture, and natural skin firmness. Delivered by experienced medical practitioners at our Mayfair, London clinic, each Profhilo Structura treatment plan is customised to your individual anatomical needs and facial structure.
Treatment Time
How long does a Profhilo Structura treatment take?
A Profhilo Structura treatment typically takes around 30 minutes.
The appointment includes preparation of the treatment area and precise placement of Profhilo Structura, making this injectable facial rejuvenation treatment quick and convenient to fit into your day.
Comfort Level
What does Profhilo Structura treatment feel like?
Profhilo Structura is generally well tolerated, with most patients experiencing only mild discomfort during treatment.
The product is carefully placed beneath the skin using a fine cannula, and a topical numbing cream may be applied where appropriate to help make the treatment as comfortable as possible.
Course Frequency
How many Profhilo Structura treatments are needed?
We usually recommend an initial course of 2 Profhilo Structura treatments, spaced approximately 4 weeks apart.
Your practitioner will assess your facial structure, degree of volume loss and individual ageing pattern to create a personalised treatment plan tailored to your desired results.
Action to Take Effect
How soon do you see results from Profhilo Structura?
Improvements from Profhilo Structura can begin to become noticeable immediately.
Results continue to develop as the treatment supports tissue remodelling within the superficial fat compartments, helping to improve facial firmness, contour and the appearance of age-related volume loss.
Duration of Effect
How long do Profhilo Structura results last?
Profhilo Structura results can typically last up to 6 months, although longevity will vary depending on your age, facial anatomy, lifestyle and individual response to treatment.
Completing the recommended treatment course and following an appropriate maintenance plan can help preserve improvements in facial structure, firmness and contour.
Maintenance
How often should you have Profhilo Structura maintenance treatments?
We generally recommend a Profhilo Structura maintenance treatment around 6 months.
Your practitioner will assess how your results develop and advise on the most appropriate maintenance schedule to help preserve facial support, contour and natural-looking rejuvenation.
Benefits of Profhilo Structura
Depending on individual anatomy and treatment goals, key benefits of Profhilo Structura may include:
Support for Facial Architecture: Helps restore the appearance of superficial facial fat compartments, addressing age-related mid-face flattening and early lower-face heaviness.
Subtle Non-Surgical Redraping: Designed to encourage a gentle lifting effect along the cheeks, lower face, and jawline without adding unnecessary or artificial volume.
Improved Skin Quality & Elasticity: Formulated to stimulate natural collagen and elastin production, which may enhance overall skin firmness, density, and texture over time.
Preserved Natural Expressions: Focuses on subtle tissue support that moves naturally with your face, helping to avoid an “overfilled” or noticeably treated appearance.
Comfortable Application: Administered using a microcannula technique designed to minimise tissue disruption and support a quick return to regular activities.
Profhilo Structura Safety, Side Effects & Aftercare
Patient safety and anatomical suitability are fundamental to every treatment plan. Prior to undergoing Profhilo Structura, a thorough medical consultation and facial assessment are conducted to evaluate individual skin quality, fat pad distribution, and general health history.
Typical Post-Treatment Experience
Temporary, mild effects near the entry points may include:
- Mild Swelling & Redness: Localised puffiness or erythema, which typically subsides over the initial days following treatment.
- Tenderness & Tightness: A temporary sensation of firmness or slight tenderness as the product integrates into the subcutaneous tissue.
- Minor Bruising: Pinpoint marks or minor bruising, particularly in proximity to delicate vascular areas.
Essential Aftercare Guidelines
- First 12–24 Hours: Refrain from applying makeup, touching or massaging the treated areas, and consuming alcohol.
- First 48 Hours: Avoid strenuous exercise, saunas, steam rooms, hot baths, or swimming pools.
- Active Skincare: Pause aggressive active ingredients (such as retinoids, AHAs/BHAs, and physical exfoliants) for at least 48 hours.
Clinical Contraindications
- Are currently pregnant or breastfeeding.
- Have active skin infections, inflammation, or cold sores near the intended injection site.
- Have a known hypersensitivity or allergy to Hyaluronic Acid.
- Present with severe autoimmune conditions or active systemic health issues that may impair healing.
Frequently Asked Questions About Profhilo Structura
Does Profhilo Structura really work?
Clinical studies suggest Profhilo Structura can improve facial volume-loss scores, wrinkles and skin firmness. In one study of 50 people, improvements were seen after the first treatment and remained evident three months after completing treatment. Earlier research also reported improvements that persisted throughout a six-month follow-up. Results vary between individuals.
Will Profhilo Structura lift my face?
Profhilo Structura may improve facial support, firmness and the appearance of mild age-related deflation, which can create a subtle lifting effect in suitable patients. However, it should not be expected to produce the same degree of lifting as surgery or treatments specifically designed for significant skin laxity. Your facial anatomy and degree of tissue loss will influence the result.
Is Profhilo Structura considered a filler?
Profhilo Structura contains hyaluronic acid but is not a conventional cross-linked dermal filler. Traditional fillers are generally used to create targeted volume or contour, whereas Profhilo Structura is designed to integrate within facial fat compartments and improve age-related tissue changes. Its consistency and behaviour are also different from conventional cross-linked HA fillers.
How quickly does Profhilo Structura work?
Some changes may be noticeable after the first Profhilo Structura treatment, but results continue to develop over the following weeks. Clinical research has reported measurable improvements after the first session, with patients commonly undergoing two treatments approximately one month apart. Your final result should therefore be assessed after completing the recommended treatment course.
How long does Profhilo Structura last?
How long Profhilo Structura lasts varies between individuals. Published clinical research has shown improvements persisting throughout a six-month follow-up after treatment. Factors such as age, facial anatomy, lifestyle and individual response can affect longevity, and your practitioner can advise when maintenance treatment may be appropriate.
Dr Preema Vig on Profhilo Structura for the Tatler Beauty & Cosmetic Surgery Guide 2025
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Dr Preema London is located on Avenfield House, 118-127 Park Lane, Mayfair, London, W1K 7AF, GB.
We’re located in the heart of London. If you’re visiting from outside elsewhere, we’re less than ten minutes by car, or 20 minutes walking from Paddington Station. Open Monday to Thursday 10 AM to 8 PM and Friday 10 AM to 7 PM.
For additional questions you can call us at 020 7221 0043
+447391153225 - WhatsApp only
Dr. Preema London Clinic
Avenfield House
118-127 Park Lane
Mayfair
London
W1K 7AF
